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br Another important reason to uncover the
2020-08-30
Another important reason to uncover the true estimate of mortality is to appropriately counsel patients. Using only a 30-day mortality estimate would severely underestimate their true risk of death following an operative resection. Others studying colorectal, lung, and 331731-18-1 resections have
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br Table br Comparison of
2020-08-30
Table 7 Comparison of the developed classifier's performance with methods in Refs. [47,65]. Method Method FNR FPR Classification Error Table 8 Comparison of the developed classifier's performance with methods in Refs. Method Method Sensitivity Specificity Accuracy Ensembl
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br colorectal pancreatic and prostate
2020-08-30
colorectal [40], pancreatic [41] and prostate cancers [13–17]. It is also associated with aggressive proliferation and metastasis of cancers [42,43]. We assessed the expression level of CDC20 in spheroid, CD44+ or chemo-resistant cells. The results supported that CDC20 pro-motes the development of
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br Materials and methods br All solvents and reagents
2020-08-30
2. Materials and methods All solvents and reagents were purchased from Sigma-Aldrich and used as received unless otherwise noted. Peptide synthesis reagents were purchased from AnaSpec (Fremont, CA). 2.1. Peptide synthesis H8R8 was synthesized by conventional solid-phase microwave as-sist
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br Results and discussion br The fibroblast component increa
2020-08-28
3. Results and discussion 3.1. The fibroblast component increases the glycolytic phenotype of tumors As a first approach to study the role of the fibroblast component of tumors, we studied the correlation of PGC-1α (master regulator of mitochondrial metabolism) and the GAPDH/MT-CO1 ratio mRN
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br Correlation of markers with survival and clinico
2020-08-28
3.3.4. Correlation of markers with survival and clinico-pathological parameters In the oral cancer cohort, based on the information available for follow up in 313 patients, 133 cases were disease free, while 91 cases developed recurrence (Supplementary Table-5). It is known that in oral cancer,
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br wide range of correlations both in the positive and
2020-08-28
wide range of correlations, both in the positive and negative ranges (P-values up to ~ 10 22, Fig. 3B). 3.2.2. The top correlated genes are associated with tumorigenesis We examined in detail the strongest correlations between expression and mutation by selecting the top 10 positive correla-
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br Table br Cumulative ambient exposure by demographics and
2020-08-28
Table 1 Cumulative ambient exposure by demographics and exposure activities. month)a month)a Male Yes Yes Yes f/cc, fibers per cubic centimeter. DK/M, do not know or missing. a Asbestos exposure based on calculation of modeled residential ambient exposure and months of res
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br the source of cancer cell lysate
2020-08-28
the source of cancer cell lysate and cancer cell membrane (Fig. 2C). The zeta potential of DOX/[email protected] was determined to be -9.6 mV. After further cloaked with the negative charged cell membrane, the zeta potential of these nanoparticles further decreased to -19.8 mV (Figure S3). Furthermore, to
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br Adjuvant chemotherapy has proved to be
2020-08-28
Adjuvant chemotherapy has proved to be of benefit in patients with stage IIA-IIIB NSCLC [25], and though its use in stage IB patients re-mains controversial, many centers offer adjuvant chemotherapy to pa-tients with tumors ≥4 cm [26]. In our cohort, 20.4% with stage IA disease surprisingly receive
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br ipsilateral mammographic surveillance following
2020-08-18
1030 ipsilateral mammographic surveillance following breast 1031 historical review, current status and future potential. 1034 Multi-image CAD employing features derived from 1037 Computerized localization of breast lesions from two views: 1041 an experimental comparison of two met
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br Data processing and statistical
2020-08-18
2.5. Data processing and statistical analysis After exporting from TargetLynx software, data were log10-trans-formed to approximate normality, and general linear models (GLMs) were used for comparison of metabolite levels between the sets of control samples from differing centers as well as bet
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br A hypercoagulable state is characteristic of
2020-08-18
A hypercoagulable state is characteristic of cancer patients, shown Corresponding authors. E-mail addresses: [email protected] (K. Pather), [email protected] (T.N. Augustine). by thrombocytosis, heightened Cyclophosphamide of platelet activation mar-kers and platelet-de
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br Feature selection rate is
2020-08-18
Feature selection rate is defined as the ratio of number of relevant features that are correctly selected to the total number of features. It is measured in terms of percentage (%). The mathe-matical formula for feature selection rate is measured as follows, number of correctly selected feature
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br miR p Transferred by BMSC Derived Exosomes
2020-08-18
miR-126-3p Transferred by BMSC-Derived Exosomes Suppresses Proliferation, Migration, and Invasion of Pancreatic Cancer Cells and Enhances Their Apoptosis In order to examine the effect of miR-126-3p in BMSC-derived exo-somes on the biological function of pancreatic cancer cells, the cell