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br another injection The sample injection volume was set
2020-08-12
another injection. The sample injection volume was set at 5 mL. Mass parameters for the analysis were the following: ESI des- olvation temperature: 350 C, desolvation gas flow: 10 L min 1, capillary voltage: 4 kV, Q1 and Q3: unit resolution; nebulizer pressure: 35 psi. The Mass was operated in
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br Implantation of patches and in vivo
2020-08-12
2.11. Implantation of patches and in vivo anti-tumor efficacy When xenograft tumor volumes reached 100 − 200 mm3, mice were divided into three groups (5 animals per group). Patches (no drug or loaded with 5-FU-RAPA-PLA-NP) were affixed to the bottoms of sub-cutaneously grafted colon tumors in a
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br Moreover As shown in
2020-08-07
Moreover, As shown in the Fig. 6, the cytosolic cytochrome c in CL 316243 treated with BHAE increased remarkably campared to the control cells (**P ≤ .01). BHAE induced elevation of lipid peroxidation rate, a marker of reac-tive oxygen species (ROS) and an increase of cytosolic cytochrome c le
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br The thermal properties of native BC
2020-08-07
The thermal properties of native BC and BC/LMN were detected by thermogravimetric analysis (TGA) (Fig. 2F). The unbound water con-tent was observed in the temperature range between 30 °C and 80 °C. The percentage weight loss was approximately 2.72% for BC and 11.45% for BC/LMNs at 520 °C. The resu
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Microtubule No br antagonist br Vinorelbine Microtubule No b
2020-08-04
1 Microtubule No31 antagonist Vinorelbine 2 Microtubule No32 antagonist DISCUSSION The purpose of this study was to determine if giving post-SRS systemic therapy to patients with Mocetinostat (MGCD0103, MG0103) metastases and controlled extracranial disease acts prophylactically
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br Appendix A Supplementary data br References br A Scarpa
2020-08-03
Appendix A. Supplementary data References A. Scarpa, S. Zappavigna, M. Marra, A. Abbruzzese, Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism, Cell Death Dis. 2 (4) (2011) e152. [10] E. Kansanen, S.M. Kuosmanen, H. Leinonen,
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br and B In the animal tumor model the DNT
2020-08-02
and B). In the animal tumor model, the DNT cell group and gem-citabine group had more apoptotic tissues than did the blank control group (Fig. 5C). Western blotting revealed that the expression of cleaved caspase-3 in the cancer cell þ DNT group was higher than that in the other two groups (Fig
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br Scheme Schematic representation of
2020-08-02
Scheme 1. Schematic representation of antibody-conjugated MNP-Si preparation. (A), Separation of Sk-BR-3 cells from PBMCs with Ab/MNP-Si. (B) Analysis with flow cytometry (C). washed with PBS 1× in a magnetic field (gradient of 0.5 T/m) for 15–20 min. Because the final product (Ab/MNP-Si) has p
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br Previous studies demonstrated that
2020-07-31
Previous studies demonstrated that aurora-A induces cell migration by upregulating the expression of the phosphatase Slingshot-1 (SSH1), which dephosphorylates cofilin and thus facilitates KX2-391 reorganization and polymerization [25,26]. Furthermore, the chaperone protein Hsp90 forms a complex w
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br reportedly involved in these processes Similarly
2020-07-29
reportedly involved in these processes [31, 42]. Similarly, stud-ies in SNU-1 gastric cancer cells confirmed the pro-apoptotic activities of SAMC [31]. SNU-I after treatment of SAMC showed a mitochondrial cytochrome c activation and an in vitro caspase-3 activity [10]. In a nude mice model i
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br Characteristics of the database used in
2020-07-28
2.2. Characteristics of the database used in this study The Raman database used comprised a total of 223 Raman spectrum samples obtained in the spectrum range of 400–1800 cm−1 wave-lengths. After final verification, the total number of samples in the Raman spectral database, whose values were o
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br Differentially In GO False br GO GO names
2020-07-28
Differentially In GO False GO GO names expressed category discovery rate antigen via MHC class II in a shaking incubator at 37 C. The tissue fragments were washed with Hank’s balanced salt solution twice, and pre-warmed incubation buffer (RPMI supplemented with colla-genase [1.5 mg/
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br Results br Overall patients of years
2020-07-27
3. Results Overall, 2837 patients of 70 years and older were included: 2523 from the Netherlands (early stage 179; T3 or Salvinorin A positive 603; ad-vanced 1639 and unknown stage 102 patients) and 314 from Moffitt Cancer Center (early stage 15, T3 or node positive 124, advanced 168 and unkno
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Furthermore for the dsDNA GE the presence of the intermediat
2020-07-27
Furthermore, for the dsDNA/GE, the presence of the intermediate form of 8-oxoguanine (8-oxoG) at E = +0.25 V is a reliable indicator that the oxidation of Pimozide is taking place (Fig. 2B) from the second scan onwards. In addition, the guanine oxidation peak current increases as the oxidative DNA
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br and colony formation assays
2020-03-24
and colony formation assays, we found that combined use of AD and vemurafenib exerted a more potent effect on suppression of cancer cell proliferation compared to either vemurafenib or AD treatment alone in CDK1-expressing colon cancer Acarbose (Fig. 6A and B). To examine whe-ther AD reverses t